BACKGROUND: Severe burn injury results in the loss of intestinal barrier function, however, the underlying mechanism remains unclear.Myosin light chain (MLC) phosphorylation mediated by MLC kinase (MLCK) is critical to the pathophysiological regulation of intestinal barrier function.We hypothesized that the MLCK-dependent MLC phosphorylation mediat
Background: Imipenem-resistant gram negative bacteria, resulting from metallo-beta-lactamase (MBLs)-producing strains have been reported Underwear to be among the important causes of nosocomial infections and of serious therapeutic problem worldwide.Because of their broad range, potent carbapenemase activity and resistance to inhibitors, these enzy
The purpose of this article is to analyze the existing algorithms of autonomous control of the integrity of the navigation field of the GLONASS system.The analysis is based on domestic materials and official foreign applications.At the beginning of the article, the concept of the integrity of the global navigation satellite system is given in the f
Brugada syndrome is an inherited cardiac channelopathy arising from mutations in voltage-gated cardiac sodium channels.Idiopathic epilepsy portrays a coalescent underlying pathophysiological mechanism pertaining to the premature excitation of neuronal voltage-gated ion channels resulting in the disruption of presynaptic neurons and the unregulated